Cytotoxic isoferulic acidamide fromMyricaria germanica(Tamaricaceae)
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چکیده
منابع مشابه
Cytotoxic isoferulic acidamide from Myricaria germanica (Tamaricaceae)
Tamgermanitin, a unique N-trans-Isoferuloyltyramine, together with the hitherto unknown polyphenolics, 2,4-di-O-galloyl-(α/β)-glucopyranose and kaempferide 3,7-disulphate have been isolated from the leaf aqueous ethanol extract of the false tamarisk, Myricaria germanica DESV. In addition, 18 known phenolics were also separated and characterized. All structures were elucidated on the basis of de...
متن کاملAdministration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice.
BACKGROUND Isoferulic acid (IFA) is a main active ingredient of the rhizoma of Cimicifuga beracleifolia, which is used frequently in Japanese traditional medicine as an anti-inflammatory drug. It has been revealed that IFA inhibits the production of macrophage inflammatory protein-2 (MIP-2), which is a murine counterpart of the chemokine family that may contribute to the pathogenesis of inflamm...
متن کاملIsoferulic acid, a new anti-glycation agent, inhibits fructose- and glucose-mediated protein glycation in vitro.
The inhibitory activity of isoferulic acid (IFA) on fructose- and glucose-mediated protein glycation and oxidation of bovine serum albumin (BSA) was investigated. Our data showed that IFA (1.25-5 mM) inhibited the formation of fluorescent advanced glycation end products (AGEs) and non-fluorescent AGE [Nε-(carboxymethyl) lysine: CML], as well as the level of fructosamine. IFA also prevented prot...
متن کاملIsoferulic acid prevents methylglyoxal-induced protein glycation and DNA damage by free radical scavenging activity
BACKGROUND Isoferulic acid (IFA), a naturally occurring cinnamic acid derivative, is a main active ingredient of the rhizoma of Cimicifuga dahurica. It has been shown various pharmacological activities. The aim of the study was to investigate the effect of IFA against MG-induced protein glycation and oxidative DNA damage. Free radical scavenging activity and the MGO-trapping abilities of IFA we...
متن کاملUse of Cytotoxic Drugs
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ژورنال
عنوان ژورنال: Plant Signaling & Behavior
سال: 2013
ISSN: 1559-2324
DOI: 10.4161/psb.22642